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1.
SNCA
[-19139bp]
2.
MAPT
3.
TMEM175
4.
ASH1L
5.
MCCC1
6.
STK39
[+24494bp]
7.
rs6430538
8.
BST1
9.
NUCKS1
[+4168bp]
10.
TMEM229B
11.
LRRK2
12.
GPNMB
13.
HLA-DQB1
[+30500bp]
14.
rs2414739
15.
BCKDK
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rs686250, chr6:32585055 (HLA-DQA1 [-10901bp])
View on:
ALSGene
Forest plot for this polymorphism
Append your own data and create meta-analysis
Polymorphism
Location (hg19)
Gene
Allele contrast
Ethnicity
# Studies
# Samples
1000G CEU
1000G CHB+JPT
Meta OR (95%CI)
I2 (95%CI)
Meta P-value
rs686250
chr6
:
32585055
HLA-DQA1
[-10901bp]
A vs. G
All: C
5
45,262
0.325 (A)
0.442 (A)
1.14 (1.06-1.23)
44 (0-80)
4.10e-04
Association studies for this polymorphism
[-]
[+]
Study
PubMed
Title
[+]
Ethnicity
Population
# Cases
# Controls
Nalls
,
2014
-
Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci
[-]
Large Scale Meta Analysis of Genome-...
[+]
C
23andMe.v3 (USA, Europe)
866
32,538
Nalls
,
2014
-
Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci
[-]
Large Scale Meta Analysis of Genome-...
[+]
C
France (IPDGC)
985
1,984
Nalls
,
2014
-
Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci
[-]
Large Scale Meta Analysis of Genome-...
[+]
C
USA (NGRC)
1,956
1,982
Nalls
,
2014
-
Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci
[-]
Large Scale Meta Analysis of Genome-...
[+]
C
USA (PROGENI-GenePD)
828
852
Nalls
,
2014
-
Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci
[-]
Large Scale Meta Analysis of Genome-...
[+]
C
USA (CHARGE-CHS)
107
3,164
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